August 2018
Coming Soon
CLINICAL CHEMISTRY
Volume 64 Number 9 September 2018
Editorials
R.P. Zahedi, C.E. Parker, and C.H. Borchers
Immuno-MALDI-TOF-MS in the Clinic
Clin Chem;64:1271
M.E. Pittman
Fecal Microbiota and Screening for Colorectal Cancer
Clin Chem;64:1273
Inspiring Minds
M. Landau
Allan Jaffe
Clin Chem;64:1275
Perspective
E.C. Keen, T.S. Crofts, and G. Dantas
Checkpoint Checkmate: Microbiota Modulation of Cancer Immunotherapy
Clin Chem;64:1280
Q&A
Moderator: A.K. Saenger; Experts: M. Berkwits, S. Carley, S. Haymond, M. Ennis-O'Connor, J. Sherbino, and S.W. Smith
The Power of Social Media in Medicine and Medical Education: Opportunities, Risks, and Rewards
Clin Chem;64:1284
Clinical Case Study
A.H. Wright, J.A. Young, B.E. Smith, and A. Saitman
The Missing Metabolite: How Unexpected Urine Drug Metabolite Patterns May Lead to False Interpretations
Clin Chem;64:1291
Commentary
M.S. Petrie
Clin Chem;64:1294
Commentary
B.O. Crews
Clin Chem;64:1294
Special Report
A.S. Whale, G.M. Jones, J. Pavšič, T. Dreo, N. Redshaw, S. Akyürek, M. Akgöz, C. Divieto, M.P. Sassi, H.-J. He, K.D. Cole, Y.-K. Bae, S.-R. Park, L. Deprez, P. Corbisier, S. Garrigou, V. Taly, R. Larios, S. Cowen, D.M. O'Sullivan, C.A. Bushell, H. Goenaga-Infante, C.A. Foy, A.J. Woolford, H. Parkes, J.F. Huggett, and A.S. Devonshire
Assessment of Digital PCR as a Primary Reference Measurement Procedure to Support Advances in Precision Medicine
Clin Chem;64:1296
Review
M. W.J. de Ronde, J.M. Ruijter, P.D. Moerland, E.E. Creemers, and S.-J. Pinto-Sietsma
Study Design and qPCR Data Analysis Guidelines for Reliable Circulating miRNA Biomarker Experiments: A Review
Clin Chem;64:1308
Articles
Automation and Analytical Techniques
P. Darebna, J. Spicka, R. Kucera, O. Topolcan, E. Navratilova, V. Ruzicka, M. Volny, P. Novak, and P. Pompach
Detection and Quantification of Carbohydrate-Deficient Transferrin by MALDI-Compatible Protein Chips Prepared by Ambient Ion Soft Landing
Clin Chem;64:1319
Cancer Diagnostics
S. Guo, L. Li, B. Xu, M. Li, Q. Zeng, H. Xiao, Y. Xue, Y. Wu, Y. Wang, W. Liu, and G. Zhang
A Simple and Novel Fecal Biomarker for Colorectal Cancer: Ratio of
Clin Chem;64:1327
S. Silva, S. Danson, D. Teare, F. Taylor, J. Bradford, A.J.G. McDonagh, A. Salawu, G. Wells, G.J. Burghel, I. Brock, D. Connley, H. Cramp, D. Hughes, N. Tiffin, and A. Cox
Genome-Wide Analysis of Circulating Cell-Free DNA Copy Number Detects Active Melanoma and Predicts Survival
Clin Chem;64:1338
Proteomics and Protein Markers
J. Boeddinghaus, R. Twerenbold, T. Nestelberger, P. Badertscher, K. Wildi, C. Puelacher, J. du Fay de Lavallaz, E. Keser, M.R. Giménez, D. Wussler, N. Kozhuharov, K. Rentsch, Ò. Miró, F.J. Martin-Sanchez, B. Morawiec, S. Stefanelli, N. Geigy, D.I. Keller, T. Reichlin, and C. Mueller for the APACE Investigators
Clinical Validation of a Novel High-Sensitivity Cardiac Troponin I Assay for Early Diagnosis of Acute Myocardial Infarction
Clin Chem;64:1347
P. Caironi, R. Latini, J. Struck, O. Hartmann, A. Bergmann, V. Bellato, S. Ferraris, G. Tognoni, A. Pesenti, L. Gattinoni, and S. Masson on behalf of the ALBIOS Study Investigators
Circulating Proenkephalin, Acute Kidney Injury, and Its Improvement in Patients with Severe Sepsis or Shock
Clin Chem;64:1361
General Clinical Chemistry
P.L. Myhre, T. Omland, S.I. Sarvari, H. Ukkonen, F. Rademakers, J.E. Engvall, T.-A. Hagve, E. Nagel, R. Sicari, J.L. Zamorano, M. Monaghan, J. D'hooge, T. Edvardsen, and H. Røsjøon behalf of the DOPPLER-CIP Study Group
Cardiac Troponin T Concentrations, Reversible Myocardial Ischemia, and Indices of Left Ventricular Remodeling in Patients with Suspected Stable Angina Pectoris: a DOPPLER-CIP Substudy
Clin Chem;64:1370
Evidence-Based Medicine and Test Utilization
A.K. Aarsand, J. Díaz-Garzón, P. Fernandez-Calle, E. Guerra, M. Locatelli, W.A. Bartlett, S. Sandberg, T. Røraas, F. Ceriotti, U.ø. Sølvik, M.S. Sylte, A. Coşkun, M. Serteser, I. Unsal, F. Tosato, M. Plebani, N. Jonker, G. Barla, and A. Carobene on behalf of the European Federation of Clinical Chemistry and Laboratory Medicine Working Group on Biological Variation
The EuBIVAS: Within- and Between-Subject Biological Variation Data for Electrolytes, Lipids, Urea, Uric Acid, Total Protein, Total Bilirubin, Direct Bilirubin, and Glucose
Clin Chem;64:1380
Molecular Diagnostics and Genetics
N.J. Wald, K.W. Lau, J.P. Bestwick, R.W. Old, W.J. Huttly, and R. Cheng
Specifying a Gold Standard for the Validation of Fetal Fraction Estimation in Prenatal Screening
Clin Chem;64:1394
Citation Classic
D.W. Bianchi
The Inadvertent Discovery of Human Fetal Cell Microchimerism
Clin Chem;64:1400
Letters to the Editor
P.A. Kavsak
External Quality Assessment Testing Near the Limit of Detection for High-Sensitivity Cardiac Troponin Assays
Clin Chem;64:1402
W.M. Loo, G.B.-B. Goh, Y. Wang, J.-M. Yuan, L. Ong, Y.Y. Dan, and W.-P. Koh
Enhanced Liver Fibrosis Score as a Predictor of Hepatocellular Carcinoma
Clin Chem;64:1404
Correction
YKL-40 and Alcoholic Liver and Pancreas Damage and Disease in 86258 Individuals from the General Population: Cohort and Mendelian Randomization Studies
Clin Chem;64:1406
Clinical Chemist
What Is Your Guess?
N.J. Rutherford, G.S. Booth, and Z. Shajani-Yi
Where Did That Peak Come From?
Clin Chem;64:1408
A.M. Strait, C.D. Brackett, and D.L. Ornstein
A Thorny Finding: Unexpected Acanthocytosis in an Elderly Patient
Clin Chem;64:1410
News & Views
J.W. Meeusen
The Heart Attack Cure: Vaccinating Against Cardiovascular Disease
Clin Chem;64:1412
Technology Corner
V.S. Kumar
A Test Not Hard to Swallow
Clin Chem;64:1413
UNVEILING THE RIGHT SIDE
R.T. Barnard
“Baby” Microscope
Clin Chem;64:1416