Table 1.

Patients' characteristics.

Disease subtypeTotal cohort (n = 156)
CM/MIS (n = 21)ISM (n = 113)Advanced SM (n = 22)
Age, years (median, range)46 (28–94)55 (26–91)68 (39–88)56 (26–94)
Sex, female/male14/764/497/1585/71
KIT D816V positivea15/21 (71%)110/113 (97%)16/22 (73%)b141/156 (90%)
KIT D816V VAF, % (median, range)0.06 (0.004–0.51)0.14 (0.002–46.9)2.43 (0.005–46.7)0.14 (0.002–46.9)
  • CM, cutaneous mastocytosis; MIS, mastocytosis in the skin.

  • a KIT D816V as assessed by ddPCR.

  • b Detailed characteristics of KIT D816V-negative advanced SM patients are presented in Table 1 of the online Data Supplement.