Table 2.

Unadjusted and adjusted HRs of cardiovascular outcomes according to hs-TnI concentrations.

End poinths-TnI concentrations, ng/L
<1.91.9–3.83.9–6.86.9–26>26
CV death, MI, or stroke
    Unadjusted HR (95% CI)Referent1.41 (1.06–1.87)1.95 (1.47–2.58)2.74 (2.08–3.61)4.13 (3.06–5.56)
    Adjusted HRa (95% CI)Referent1.30 (0.97–1.74)1.57 (1.17–2.10)1.92 (1.43–2.58)2.70 (1.96–3.71)
CV death
    Unadjusted HR (95% CI)Referent3.27 (1.18–9.12)6.69 (2.45–18.27)15.37 (5.71–41.38)22.82 (8.34–62.48)
    Adjusted HRa (95% CI)Referent2.83 (1.01–7.90)4.41 (1.61–12.14)7.61 (2.78–20.84)9.99 (3.57–27.97)
MI
    Unadjusted HR (95% CI)Referent1.64 (1.05–2.56)2.62 (1.70–4.05)3.47 (2.26–5.32)5.83 (3.71–9.17)
    Adjusted HRa (95% CI)Referent1.51 (0.95–2.41)1.97 (1.25–3.12)2.21 (1.39–3.50)3.40 (2.09–5.54)
Stroke
    Unadjusted HR (95% CI)Referent1.05 (0.71–1.55)1.07 (0.73–1.59)1.19 (0.81–1.75)1.39 (0.87–2.23)
    Adjusted HRa (95% CI)Referent1.01 (0.68–1.50)1.07 (0.72–1.61)1.23 (0.81–1.87)1.49 (0.89–2.49)
  • a Variables included in the multivariate analysis: age, sex, diabetes mellitus, hypertension, hyperlipidemia, current smoker, CAD, cerebrovascular disease, PAD, heart failure, eGFR, BNP, and hs-CRP.