Table 2.

Rule-out results using different baseline troponin I concentrations without ECG information.a

≤ Cutoff, ng/LAMIType 1 AMI
NPVSensitivityFNb + TN% of all Non-AMINPVSensitivityFN + TN% of all Non-AMI
1.9, LoD99.5 (97.2–100.0)99.4 (96.9–100.0)1 + 198 = 19925.499.5 (97.2–100.0)99.1 (95.1–100.0)1 + 198 = 19925.4
299.5 (97.3–100.0)99.4 (96.9–100.0)1 + 206 = 20726.499.5 (97.3–100.0)99.1 (95.1–100.0)1 + 206 = 20726.4
399.3 (97.4–99.9)98.9 (96.0–99.9)2 + 276 = 27835.499.3 (97.4–99.9)98.2 (93.7–99.8)2 + 276 = 27835.4
498.3 (96.4–99.4)96.6 (92.8–98.8)6 + 352 = 35845.298.9 (97.1–99.7)96.4 (91.1–99.0)4 + 352 = 35645.2
597.4 (95.5–98.7)93.9 (89.3–96.9)11 + 419 = 43053.898.8 (97.3–99.6)95.5 (89.9–98.5)5 + 419 = 42453.8
5.2, 10% CV97.3 (95.3–98.6)93.3 (88.6–96.5)12 + 430 = 44255.298.9 (97.3–99.6)95.5 (89.9–98.5)5 + 430 = 43555.2
697.1 (95.2–98.4)92.2 (87.2–95.7)14 + 475 = 48961.098.5 (97.0–99.4)93.8 (87.5–97.5)7 + 475 = 48261.0
796.2 (94.2–97.6)88.3 (82.6–92.6)21 + 526 = 54767.598.3 (96.8–99.2)92.0 (85.3–96.3)9 + 526 = 53567.5
896.3 (94.4–97.6)87.7 (82.0–92.1)22 + 566 = 58872.798.4 (97.0–99.3)92.0 (85.3–96.3)9 + 566 = 57572.7
995.6 (93.7–97.1)84.9 (78.8–89.8)27 + 586 = 61375.298.2 (96.7–99.1)90.2 (83.1–95.0)11 + 586 = 59775.2
1094.9 (92.9–96.4)81.6 (75.1–87.0)33 + 610 = 64378.397.8 (96.3–98.8)87.5 (79.9–93.0)14 + 610 = 62478.3
27, 99th Pctl.91.3 (89.1–93.1)61.5 (53.9–68.6)69 + 720 = 78992.495.7 (94.0–97.1)71.4 (62.1–79.6)32 + 720 = 75292.4
  • a CIs are 95%.

  • b FN, false negative; TN, true negative; pctl, percentile.