Table 3.

Rule-out of AMI using hsTnI and ECG information.a

≤Cutoff, ng/LAMIType 1 AMI
NPVSensitivityFNb + TN% of all Non-AMINPVSensitivityFN + TN% of all Non-AMI
1.9, LoD100.0 (96.5–100.0)100.0 (96.9–100.0)0 + 158 = 15820.6100.0 (96.5–100.0)100.0 (95.1–100.0)0 + 158 = 15820.6
2100.0 (96.7–100.0)100.0 (96.9–100.0)0 + 165 = 16521.5100.0 (96.7–100.0)100.0 (95.1–100.0)0 + 165 = 16521.5
3100.0 (97.5–100.0)100.0 (96.9–100.0)0 + 218 = 21828.4100.0 (97.5–100.0)100.0 (95.1–100.0)0 + 218 = 21828.4
499.3 (97.4–99.9)98.9 (96.0–99.9)2 + 274 = 27635.799.6 (98.0–100.0)99.1 (95.1–100.0)1 + 274 = 27535.7
598.5 (96.5–99.5)97.2 (93.5–99.1)5 + 321 = 32641.999.7 (98.3–100.0)99.1 (95.1–100.0)1 + 321 = 32241.9
5.2, 10% CV98.5 (96.5–99.5)97.2 (93.5–99.1)5 + 327 = 33242.699.7 (98.3–100.0)99.1 (95.1–100.0)1 + 327 = 32842.6
698.4 (96.4–99.4)96.6 (92.7–98.7)6 + 358 = 36446.799.4 (98.0–99.9)98.2 (93.6–99.8)2 + 358 = 36046.7
798.0 (96.1–99.1)95.5 (91.2–98.0)8 + 388 = 39650.699.2 (97.8–99.8)97.3 (92.3–99.4)3 + 388 = 39150.6
898.1 (96.3–99.2)95.5 (91.2–98.0)8 + 413 = 42153.899.3 (97.9–99.9)97.3 (92.3–99.4)3 + 413 = 41653.8
997.4 (95.5–98.7)93.8 (89.1–96.8)11 + 420 = 43154.898.8 (97.3–99.6)95.5 (89.8–98.5)5 + 420 = 42554.8
1096.8 (94.8–98.3)92.0 (87.0–95.6)14 + 430 = 44456.198.4 (96.7–99.4)93.7 (87.4–97.4)7 + 430 = 43756.1
27, 99th Pctl.95.1 (92.8–96.8)86.4 (80.4–91.1)24 + 464 = 48860.597.7 (95.9–98.8)90.1 (83.0–94.9)11 + 464 = 47560.5
  • a CIs are 95%.

  • b FN, false negative; TN, true negative; pctl, percentile.