Table 4. Multivariate analysis of overall survival: CTC status (CellSearch and EPISPOT assays).
VariableCategoriesHazard ratio95% CIP
HER2 status0.0364
Positive1
Negative2.241(1.052–4.772)
CTC status (CellSearch and EPISPOT assays)0.0211
Double negative1
EPISPOT14.479(1.794–116.839)
CellSearch + EPISPOT22.649(2.787–184.081)
CellSearch26.883(3.168–228.143)
Therapeutic setting0.005
First line1
Second line4.539(1.636–12.594)
Third line or more4.155(1.652–10.454)
Estrogen receptor status0.0001
Positive1
Negative4.683(2.168–10.114)