Table 2. One-sided 99th percentiles for populations studied.a
PopulationAssay
cTnI Siemens Ultrahs-cTnT RochecTnI Beckman AccuI
99th Percentile all99th Percentile male99th Percentile femaleP, male vs female99th Percentile all, n99th Percentile male99th Percentile femaleP, male vs female99th Percentile all99th Percentile male99th Percentile femaleP, male vs female
All (n = 545, 258 male)39.038.047.00.5929.937.227.70.001866.880.962.2<0.0001
Questionnaire screened [n = 340 (62.4%) (157 male)]38.637.442.00.4920.023.213.60.00166.479.063.4<0.0003
Questionnaire screened plus BP ≤140/90 [n = 266 (48.8%) (120 male)]39.936.444.20.09319.123.813.30.002159.080.262.10.0041
Questionnaire screened plus normal ECG [n = 291 (53.3%) (132 male)]39.237.743.40.2521.623.713.90.020369.484.565.10.0041
Questionnaire screened plus NT-proBNP within reference interval [n = 330 (62.9%) (163 male)]38.737.542.30.3916.722.812.80.001167.279.963.80.0006
Questionnaire screened plus normal LVEF [n = 318 (58.3%) (143 male)]38.837.642.40.4517.321.913.70.003160.982.156.80.0004
Questionnaire screened plus eGFR >60 [n = 314 (57.6%) (144 male)]38.937.642.70.5514.421.513.80.006968.381.964.30.0011
Normals [n = 200 (36.7%)]41.00.7614.40.029543.80.0430
Manufacturers claimb40.014.040
  • a All measurements are in ng/L.

  • b Manufacturers' claimed 99th percentile limit taken from the manufacturers' kit datasheets. No data were available in the kit datasheets regarding male and female differences.