Table 1.

Vitamins, metabolites, plasma holoTC, and serum creatinine in relation to hormone therapy.1

MarkersOC (age range, 18–40 years)HRT (age range, 41–65 years)
Users (n = 54)Controls (n = 81)Users (n = 51)Controls (n = 78)
Serum cobalamin, pmol/L2542 (67–477)354 (168–711)331 (159–623)349 (146–1209)
Plasma holoTC, pmol/L552 (12–108)74 (31–218)82 (44–179)80 (26–1541)
holoTC/cobalamin ratio0.21 (0.07–0.43)0.21 (0.10–0.60)0.26 (0.12–0.52)0.23 (0.11–1.27)
Plasma MMA, μmol/L0.14 (0.10–0.34)0.13 (0.08–0.26)0.16 (0.09–0.29)0.17 (0.09–0.40)
Plasma tHcy, μmol/L7.8 (4.8–63.1)7.1 (4.1–21.2)8.4 (5.2–19.0)8.6 (5.6–16.0)
Serum folate, nmol/L13.3 (2.7–60.7)15.7 (6.5–96.8)16.4 (5.4–87.4)16.2 (5.1–51.2)
WB folate3, nmol/L251 (81–485)240 (74–585)268 (86–506)256 (79–843)
Serum creatinine, μmol/L76 (66–87)74 (60–90)78 (62–97)76 (60–108)
  • 1 Data shown as median (range).

  • 2 P <0.01.

  • 3 WB folate, whole-blood cell folate.