Table 2.

Genotype assessment of RASSF1A sequences in maternal blood cells, placenta (or CVS), and plasma DNA with and without (only for 3rd-trimester cases) methylation-sensitive restriction enzyme digestion.1

A. 3rd-trimester pregnant women.
No. of cases2Genotype
Blood cellsUndigested plasmaPlacentaDigested plasma
5AAAAAAAA
11ACACACAC
12CCCCCCCC
3AAAA3ACAC
3ACACAAAA
7ACACCCCC
2CCCC3ACAC
B. 1st-trimester pregnant women.
No of cases2Genotype
Blood cellsCVSDigested plasma
3ACACAC
6CCCCCC
1AAACAC
3ACAAAA
3ACCCCC