Table 2.

Genotype assessment of RASSF1A sequences in maternal blood cells, placenta (or CVS), and plasma DNA with and without (only for 3rd-trimester cases) methylation-sensitive restriction enzyme digestion.¹

A. 3rd-trimester pregnant women.
No. of cases²	Genotype
No. of cases²	Blood cells	Undigested plasma	Placenta	Digested plasma
5	AA	AA	AA	AA
11	AC	AC	AC	AC
12	CC	CC	CC	CC
3	AA	AA³	AC	AC
3	AC	AC	AA	AA
7	AC	AC	CC	CC
2	CC	CC³	AC	AC

B. 1st-trimester pregnant women.
No of cases²	Genotype
No of cases²	Blood cells	CVS	Digested plasma
3	AC	AC	AC
6	CC	CC	CC
1	AA	AC	AC
3	AC	AA	AA
3	AC	CC	CC