Table 4.

Reported serum concentrations in healthy persons of major serum proteins with unpaired Cys residues (18)(35)(36)(37).

ProteinMolecular WeightConcentration, mg/LConcentration, μmol/LUnpaired ResidueTotal Cysteines
Albumin66 40035 000–52 000527–7833435
Major globulins
 Apolipoprotein A-II8 691200–55023–6361
 α1-Antitrypsin (α1-proteinase inhibitor)55 000900–2 00018–402321
 Transthyretin (prealbumin)55 000 (4 subunits)200–40015–30104 (1 per subunit)
 Immunoglobulin A160 000700–4 0004–24variablevariable
 α1-Acid glycoprotein (gene 2)40 000160–4004–10149 (estimated)5
 α1-Antichymotrypsin68 000∼500∼72381
 Apolipoprotein D29 00050–2002–81165
Sum of major globulins∼75–175