Content of thiol-containing amino acids and peptides released from specific protein preparations by reduction.
Fraction | Protein, g/L | Cys, μmol/L | Hcy, μmol/L | CysGly, μmol/L | Glutathione, μmol/L |
---|---|---|---|---|---|
Transferrin | 10 | 1.0 | ND | 0.14 | ND |
HDL | 10 | 38.9 | 0.43 | 3.16 | 1.80 |
IgG | 10 | 3.0 | 0.14 | 0.36 | ND |
α1-Acid glycoprotein | 10 | 92.4 | 2.58 | 9.59 | 13.0 |
Corrected to usual serum concentrations | |||||
Transferrin | ∼3 | 0.3 | ND | 0.04 | ND |
HDL | ∼2 | 7.8 | 0.08 | 0.63 | 0.36 |
IgG | ∼12 | 3.6 | 0.17 | 0.43 | ND |
α1-Acid glycoprotein | ∼0.8 | 7.4 | 0.2 | 0.77 | 1.0 |
After loading with CysGly | |||||
Transferrin | 10 | 0.8 | ND | 0.9 | ND |
HDL | 10 | 1.6 | 0.05 | 30.0 | ND |
IgG | 10 | 0.6 | ND | 4.6 | ND |
α1-Acid glycoprotein | 10 | 12.4 | 1.78 | 76.9 | ND |