Table 1. Clinical characteristics of patients with and without increased urinary catalytic iron.a
Without increased iron (n = 231)With increased iron (n = 276)P
Urinary catalytic iron, nmol/mg83.3 (90.5)623.6 (405.6)<0.0001
Urinary isoprostane, pmol/mmol111.1 (156.4)101.4 (235.0)0.76
Age, years64.5 (5.6)64.5 (5.8)0.94
Males/female sex, n123/108140/1360.57
Approximate DM duration, years13.1 (7.5)12.8 (7.4)0.63
UALB/Ucreat,b μg/mg26.2 (128.3)18.3 (32.9)0.37
Plasma creatinine, mg/dL0.8 (0.2)0.8 (0.2)0.46
Hemoglobin A1c, %8.2 (1.1)8.2 (1.1)0.47
Systolic BP, mmHg136.6 (14.8)135.6 (16.7)0.5
Diastolic BP, mmHg76.9 (9.5)76.3 (10.1)0.49
Total cholesterol, mg/dL191.8 (44.4)197.1 (42.8)0.18
LDL cholesterol, mg/dL110.7 (35.0)114.7 (37.2)0.22
HDL cholesterol, mg/dL42.8 (11.1)43.5 (12.2)0.49
BDI/Ucreat, nmol/mg95.6 (72.1)846.3 (593.4)<0.0001
  • a Data are presented as the mean (SD) except for the sex data.

  • b UALB/Ucreat, urine microalbumin–urine creatinine ratio; BP, blood pressure; BDI/Ucreat, urine bleomycin-detectable iron–urine creatinine ratio.