Table 1.

Specificities of lectins and carbohydrate-reactive antibodies.

Detection reagent and general reactivityLectin or antibodyCarbohydrate structural motifReferences
Lectin
 α/β-d-Galactosyl specificAgaricus bisporus (ABA)Galβ1-3GalNAc-serine/threoninePresant and Kornfeld (120)
Allomyrina dichotoma (AlloA)NeuAcα2-3Galβ1-4GlcNAcSueyoshi et al. (121)
Artocarpus integrifolia (Jacalin)Galβ1-3GalNAc, Galα1-6GalAhmed and Chatterjee (122)
Erythrina christagalli (ECA)Galβ1-4GlcNAcKaladas et al. (123)
Arachis hypogaea (peanut, PNA)Galβ1-3GalNAcSwamy et al. (124)
d-N-Acetylgalactosaminyl specificDolichos biflorus (DBA)GalNAcα1-3GalNAcTorres et al. (125)
GalNAcα1-3GalPiller et al. (126)
Glycine max (soybean, SBA)GalNAcα1-3GalNAcPiller et al. (126)
GalNAcα/β1-3/4Gal
Helix pomatia (HPA)α-GalNAc, GalNAcβ1-4GalTorres et al. and Piller et al. (125)(126)
Phaseolus lunatus (lima bean, LBA)GalNAcα1-3 (Fucα1-2)GalβRoberts and Goldstein (127)
GalNAcα1-2Galβ
Wisteria floribunda (WFA)GalNAcα1-3GalNAcTorres et al. (125)
GalNAcβ1-3/4GalPiller et al. (126)
Vicia villosa (VVA)GalNAc-SerShen et al. (128)
d-N-Acetylglucosamine specificDatura stramonium (DSA)(GlcNAcβ1-4)2-4, Galβ1-4GlcNAcCrowley et al. (129)
Griffonia simplifilica II (GS-II)GlcNAcα1-4Galβ1-4GlcNAcWood et al. (130)
Lycopersicon esculentum (Tomato)(GlcNAcβ1-4)1-4Nachbar et al. (131)
Triticum vulgare (wheat germ, WGA)(GlcNAcβ1-4)2-5, Neu5AcAllen et al. and Peters et al. (132)(133)
Manβ1-4GlcNAcβ1-4GlacNAcYamamoto et al. (134)
d-Mannosyl specificCanavalia ensiformis (Con A)Branched N-linked hexa-saccharideDebray et al. (135)
Galanthus nivalis (GNA)Manα1-3ManShibuya et al. (136)
Lens culinaris (LCA)Fucα1-6GlcNAc-N-Asn containing N-linked oligosaccharidesDebray et al. (135)
Pisum sativum (PSA)Fucα1-6GlcNAc-N-Asn containing N-linked oligosaccharidesDebray et al. (135)
 α-l-Fucosyl specificAleuria aurantia (AAL)Fucα1-6/3GlcNAcKornfeld et al. (137)
Anguilla anguilla (AAA)α-l-FucDebray and Montreuil (138)
Lotus tetragonolobus (LCA)Fucα1-2Galβ1-4 (Fucα1-3)GlcNAcHorejsi et al. (139)
Ulex europaeus I (UEA I)Fucα1-2GalβPereira and Kabat (140)
 Neu5Ac specificCancer antennarius (CAA)4/9-O-Ac-Neu5AcSughii et al. (141)
Maackia amurensis II (MAA II)Neu5Acα2-3Galβ1-4Glc/GlcNAcRavindranath et al. (142)
Sambucus nigra (SNA)Neu5Acα2-6Gal/GalNAcWang and Cummings (143)
 Lectins with complex specificitiesCicer arietinum (CPA)Complex structure, binding inhibited by human IgM, fetuinKolberg et al. (144)
Euonymus europaeus (EEA)Galα1-3(Fucα1-2)Galβ1-3/4GlcNAcPetryniak and Goldstein (145)
Phaseolus vulgaris erythroagglutinating (PHA-E)N-linked bi-antennaryCummings and Kornfeld (146)
Phaseolus vulgaris leukoagglutinating (PHA-L)N-linked tri/tetra-antennaryCummings and Kornfeld (146)
Continued on page 229