Table 1.

Prospective studies of apo B and LDL-P: comparison with LDL-C.

StudyComparisonapo BLDL-CMatching and/or adjustment variables
Salonen et al. (48)NS1No dataSex, age, TC, smoking, CVD history, mean arterial BP
Stampfer et al. (49)Quintile 5 vs 12.50 (1.31–4.75)No LDL-CAge, smoking
Sigurdsson et al. (50)1 SD1.32 (P < 0.001)No LDL-C
Coleman et al. (51)Tertile 3 vs 12.4 (1.0–4.7)No LDL-C
Wald et al. (52)Quintile 5 vs 17.02 (3.96–12.5)No LDL-C
Lamarche et al. (39)1 SD1.44 (1.22–1.67)No LDL-CAge, SBP, diabetes, smoking, medications
Cremer et al. (53)Quintile 5 vs 18.7 (5.2–14.5)13.2 (7.4–23.6)Age, smoking, alcohol use, family history
Sweetnam et al. (54)1 SD1.20 (1.05–1.37)No dataDBP, smoking, BMI, ischemia at baseline
Gotto et al. (46)Baseline 1 year treatmentP = 0.002NSTreatment group, age, sex, marital status, hypertension, smoking, family history
P < 0.001NS
Walldius et al. (38)1 SDM, 1.33 (1.17–1.51); W, 1.53 (1.25–1.88)M, 1.14 (1.01–1.28); W, 0.85 (0.69–1.05)Age, TC, TG, apo B, LDL-C
Simons et al. (55)1 SD1.28 (1.15–1.42)1.28 (1.14–1.42)Age, BMI, sex, family history, SBP, BP medications, smoking, diabetes, TC, HDL-C, TG
Sharrett et al. (45)Quintile 5 vs 1M, 2.4; W, 2.8M, 2.5; W, 2.7Smoking, BP, diabetes, medications
Talmud et al. (41)1 SD1.42 (1.19–1.70)1.31 (1.12–1.52)Age, clinic, HDL-C
Blake et al. (44)Quartile 4 vs 12.43 (1.23–4.82)2.06 (1.03–4.12)Age, smoking, treatment group
Shai et al. (42)1 SD, quintile 5 vs 11.8 (1.5–2.2); 4.7 (2.5–8.9)1.4 (1.2–1.6); 2.7 (1.6–4.6)Fasting status, age, smoking, month of blood draw
Jiang et al. (43)Quartile 4 vs 12.31 (1.23–4.35)1.74 (0.99–3.06)Age, BMI, family history of MI, smoking, physical activity, alcohol intake, fasting status, hypertension, aspirin use, Hb A1c
St-Pierre et al. (40)Tertile 3 vs 17 years, 2.4 (1.5–3.8); 13 years, 1.6 (1.0–2.5)No dataAge, BMI, SBP, diabetes, smoking, medications, TG, HDL-C
Ridker et al. (47)Quintile 5 vs 12.50 (1.68–3.72)1.62 (1.17–2.25)Age, smoking, BP, diabetes, BMI
Meisinger et al. (56)1 SDM, 1.49 (1.25–1.78); W, 1.73 (1.32–2.27)M, 1.49 (1.25–1.78); W, 1.79 (1.40–2.30)Diabetes, smoking, BMI, hypertension, age, alcohol use
Pischon et al. (58)Quintile 5 vs 12.98 (1.76–5.06)2.07 (1.24–3.45)Age, smoking, month of blood draw, BMI, family history of premature MI, diabetes, alcohol use, physical activity
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