Table 2.

Prospective studies of LDL-P in comparison with LDL-C.

StudyComparisonLDL-PLDL-CMatching and/or adjustment variables
Blake et al. (44)Quartile 4 vs 14.17 (1.96–8.87)2.06 (1.03–4.12)Age, smoking, treatment group
Kuller et al. (67)Quartile 4 vs 1M, NS; W, 2.59M, NS1; W, 3.34Age, race
Rosenson et al. (68)Above vs below median2.1 (0.7–5.8)1.4 (0.5–3.9)Age, race, baseline lumen diameter
El Harchaoui et al. (69)Quartile 4 vs 11.78 (1.34–2.37)1.22 (0.92–1.61)Smoking, SBP, LDL-C or LDL-P
Otvos et al. (66)Baseline, 1 SD1.20 (1.05–1.37)1.10 (0.97–1.25)Treatment group, age, hypertension, smoking, BMI, diabetes
On-trial, 1 SD1.28 (1.12–1.47)1.08 (0.95–1.23)
Cromwell et al. (70)1 SDM, 1.24 (1.10–1.39); W, 1.33 (1.17–1.50)M, 1.06 (0.94–1.20); W, 1.18 (1.02–1.37)Age, SBP, DBP, smoking, medications
Mora et al. (59)Quintile 5 vs 12.51 (1.91–3.30)1.74 (1.40–2.16)