Table 4.

Cox proportional hazard models for assessing combinations of IL-6, MCP-1, and NT-proBNP for death/HF at 8 years.

ModelMarkers in modelLikelihood ratioDegrees of freedomModels comparedP value
1IL-6 alone16.51Reference
2IL-6, MCP-119.322 vs 10.094
3IL-6 + MCP-1 + interactions22.733 vs 20.066
4IL-6, NT-proBNP36.424 vs 1<0.001
5IL-6 + NT-proBNP + interaction40.135 vs 40.056
6IL-6, MCP-1, NT-proBNP41.436 vs 2; 6 vs 4<0.001; 0.025
7IL-6, MCP-1, NT-proBNP + 2-way interactions43.667 vs 60.542