Table 2.

Coffee consumption and plasma vitamin levels.1

VitaminCoffee, cups/dayAllMenWomen
Plasma concentration2DifferencePlasma concentration2DifferencePlasma concentration2Difference
%% of SD%% of SD%% of SD
Folate, nmol/L016.2RefRef14.9RefRef17.4RefRef
1–315.2−5.7−10.114.3−3.9−7.616.2−6.9−11.7
≥414.2−11.7−20.213.3−10.1−19.215.1−13.7−22.3
P for trend (ANCOVA)<0.001<0.001<0.001
PLP, nmol/L055.8RefRef54.9RefRef56.5RefRef
1–352.0−6.4−9.652.9−2.9−5.551.2−9.4−12.5
≥447.8−14.1−20.446.9−14.4−23.748.8−13.9−18.7
P for trend (ANCOVA)<0.001<0.001<0.001
Riboflavin, nmol/L011.3RefRef10.6RefRef12.1RefRef
1–311.0−2.2−2.710.82.12.711.3−6.7−7.3
≥410.7−5.5−6.610.1−4.9−5.711.3−6.8−7.4
P for trend (ANCOVA)0.010.020.16
Cobalamin, pmol/L0310RefRef307RefRef312RefRef
1–3306−0.8−2.2305−0.6−2.0309−0.9−2.7
≥4307−0.5−1.4303−1.0−3.3311−0.2−0.4
P for trend (ANCOVA)0.750.440.83