Table 1.

Sample characteristics.1

Males (n = 592)Females (n = 614)
Age, mean (range)38.1 (18–63)38.2 (18–67)
Body mass index, mean (range)24.8 (17.7–40.4)24.0 (16.4–43.7)
Fasting glucose4.7 (2.7–9.3)4.9 (2.8–13.0)
Summer, %38.139.0
Smoking, n (%)198 (33.4)200 (32.5)
No. of MZ234244
Estrogen use, n (%)124 (20.1)
Systolic BP, mmHg (SD)120.6 (13.5)114.0 (14.5)
Diastolic BP, mmHg (SD)70.9 (10.3)68.2 (10.4)
Total cholesterol, mmol/L (SD)5.5 (1.2)5.5 (1.2)
Genotype distribution
MTHFRCCCTTTCCCTTT
(n = 1136)2692355128824251
MTRAAAGGGAAAGGG
(n = 1126)3761532337717720
NNMTGGGAAAGGGAAA
(n = 1095)3801342536017818