Table 2.

Baseline characteristics of the study hospital survivors and nonsurvivors (n = 255).

SurvivorsNonsurvivorsP
n18867
Age, years58 (47–70)65 (56–76)<0.001
Male sex136 (72)40 (60)0.06
Cardiovascular comorbidity39 (21)27 (40)0.002
Length of ICU stay, days5.8 (3.1–11.0)6.1 (3.1–12.8)0.42
Positive blood culture54 (29)17 (25)0.6
Primary site of infection
 Lung76 (40)30 (45)0.5
 Intra-abdominal59 (31)23 (34)0.7
 Urinary tract9 (5)2 (3)0.7
 Central nervous system6 (3)0 (0)0.3
 Soft tissue21 (11)4 (6)0.3
Trauma4 (2)2 (3)0.7
Hospital-acquired infection58 (31)27 (40)0.16
Ventilatory treatment131 (70)55 (82)0.05
Fluids in the first 24 h in ICU, mL4550 (2580–6890)4410 (3330–7200)0.46
Vasoactive medication on day 1138 (73)55 (82)0.16
Maximum lactate in the first 24 h, mmol/L2.0 (1.3–3.0)3.7 (2.0–5.6)<0.001
Creatinine clearance, mL/min70 (44–111)45 (23–90)0.001
APACHE II score22 (17–28)28 (22–36)<0.001
SAPS II score40 (30–50)54 (40–64)<0.001
SOFA score on day 18 (6–10)10 (7–13)<0.001
Max SOFA score8 (6–11)11 (8–15)<0.001