Table 3.

Incidence density and adjusted RR for incident diabetes and hypertension from year 0 to year 15 by serum GGT at baseline in the CARDIA Study, 1985–2001.

OutcomeGGT at year 0P for trend
<25%25% to <50%50% to <75%75% to <90%≥90%
Incident cases of diabetes1
 Cases/person-years11/11 55232/19 72937/19 87935/726242/6127
 Incidence density, per 1000 person-years1.01.61.94.86.9
 Adjusted RR
  Model 121.01.6 (0.8–3.3)1.7 (0.9–3.4)4.0 (2.0–8.1)5.5 (2.7–11.1)<0.01
  Model 231.01.7 (0.8–3.3)1.8 (0.9–3.6)4.2 (2.1–8.5)6.1 (3.0–12.3)<0.01
  Model 341.01.5 (0.8–3.0)1.4 (0.7–2.7)2.6 (1.3–5.3)3.3 (1.6–6.8)<0.01
 Model 45 1.01.5 (0.7–3.4)1.5 (0.7–3.4)2.6 (1.2–6.0)2.9 (1.2–6.9)0.002
Incident cases of hypertension6
 Cases/person-years65/11 271150/19 043240/18 762133/6394120/5310
 Incidence density, per 1000 person-years5.87.912.820.822.6
 Adjusted RR
  Model 121.01.2 (0.9–1.6)1.7 (1.2–2.2)2.3 (1.7–3.2)2.3 (1.7–3.2)<0.01
  Model 231.01.2 (0.9–1.6)1.6 (1.2–2.2)2.3 (1.7–3.2)2.3 (1.7–3.2)<0.01
  Model 341.01.2 (0.9–1.6)1.5 (1.1–2.0)2.0 (1.5–2.7)1.9 (1.4–2.7)<0.01
  Model 451.01.3 (0.9–1.8)1.5 (1.1–2.1)1.9 (1.4–2.8)1.5 (1.0–2.2)0.003