Table 2.

Adjusted mean1 values for inflammatory and/or oxidative stress markers by year 0 and/or year 10 GGT in the CARDIA Study, 1985–2001.

GGT at year 0Difference,2 %P for trend
<25%25% to <50%50% to <75%75% to <90%≥90%
Fibrinogen (year 5), mg/L260726072634267427285<0.001
(n = 758)(n = 1268)(n = 1297)(n = 471)(n = 414)
Uric acid (year 15), mg/L464850525213<0.001
(n = 639)(n = 1099)(n = 1083)(n = 411)(n = 339)
CRP (year 15),3 mg/L1.31.41.41.61.731<0.001
(n = 642)(n = 1101)(n = 1085)(n = 411)(n = 340)
F2-Isoprostanes (year 15), ng/L56.059.159.360.963.3130.003
(n = 535)(n = 921)(n = 909)(n = 332)(n = 282)
GGT at year 10Difference,2 %P for trend
<25%25% to <50%50% to <75%75% to <90%≥90%
Uric acid (year 15), mg/L454750525420<0.001
(n = 677)(n = 901)(n = 868)(n = 511)(n = 311)
CRP (year 15),3 mg/L1.21.41.51.71.633<0.001
(n = 676)(n = 905)(n = 869)(n = 512)(n = 311)
F2-Isoprostanes (year 15), ng/L54.757.659.362.468.225<0.001
(n = 572)(n = 757)(n = 738)(n = 427)(n = 253)