Table 4.

Sensitivity and specificity (95% confidence intervals) for CDTect (units/L), Bio-Rad %CDT TIA, and GGT at the specified cutoffs for males and females.1

MalesFemales
SensitivitySpecificitySensitivitySpecificity
CDTect,2(units/L)0.73 (0.65–0.80)0.91 (0.85–0.95)0.41 (0.29–0.54)0.90 (0.80–0.96)
Bio-Rad %CDT TIA30.73 (0.68–0.78)0.96 (0.92–0.99)0.52 (0.42–0.63)0.94 (0.88–1.00)
GGT40.65 (0.57–0.73)0.89 (0.82–0.94)0.54 (0.42–0.67)0.97 (0.90–1.00)
CDTect (units/L) with GGT0.90 (0.84–0.95)0.81 (0.73–0.87)0.75 (0.63–0.85)0.87 (0.76–0.94)
Bio-Rad %CDT TIA with GGT0.90 (0.87–0.93)0.84 (0.78–0.90)0.76 (0.67–0.85)0.91 (0.84–0.98)
  • 1 Based on 199 alcoholics (132 males and 67 females) and 199 matched social drinkers.

  • 2 CDTect cutoffs are 20 units/L for men and 26 units/L for women.

  • 3 Bio-Rad %CDT TIA cutoff is 2.6% for both men and women.

  • 4 GGT cutoff is 54 U/L for both men and women.