Table 3.

Examples of potential improved clinical benefit.

Diagnostic strategy
“Rule out” of urinary tract infection
Triage of patients with acute chest pain
Screening tests
Therapeutic strategy
Improved compliance with therapy
Bone markers vs DEXA and bisphosphonate therapy in patients with osteoporosis
POCT for anticonvulsant drugs
POCT for HbA1C
Reduced risk of toxicity of therapy
Cyclosporin monitoring in transplant patients
Monitoring of lithium therapy
Clinical outcome
Reduced rate of onset of complications
Regular monitoring of glucose in patients with diabetes mellitus (including gestational diabetes)
Detection of microalbuminuria in patients with diabetes
Monitoring of proteinuria in patients at risk of preeclampsia
Screening tests
Testing for substance overdose, e.g., acetaminophen, salicylate