Table 1.

Markers of bone turnover in prostate cancer patients with bone metastases compared with healthy males.a

Biochemical markersHealthy males1Patients with bone metastases1
Total ALP, U/L156 (102–234)2732 (132–3540)b,c
B/I, U/L4.2 (2.4–9.0)9.0 (3.0–54)3
B1, U/L23 (11–44)101 (14–756)3
B2, U/L57 (29–98)526 (41–2824)3
B1/B2 ratio0.42 (0.23–0.81)0.20 (0.08–0.57)3
Osteocalcin, μg/L3.0 (0.6–4.3)4.9 (0.6–15.9)3
ICTP, μg/L3.1 (1.8–4.8)10.2 (2.5–40.0)3