Table 4.

Risk of death from cancer by GGT quartile.a

Person-yearsEvents, nMortality rate (per 10000 person-years)Age · sex- adjusted HR (95% CI)Multivariate HR (95% CI)b
Model 1Model 2Model 3
GGT quartile, IU/L
    1–12291168.4642.21.00 (reference)1.00 (reference)1.00 (reference)1.00 (reference)
    13–19260717.4783.00.92 (0.66–1.30)1.10 (0.76–1.59)1.11 (0.77–1.60)1.13 (0.78–1.63)
    20–34275813.71174.21.10 (0.79–1.53)1.37 (0.95–1.98)1.38 (0.95–1.99)1.46 (1.01–2.11)
    ≥35273610.31314.81.24 (0.89–1.73)1.44 (0.97–2.15)1.44 (0.98–2.15)1.57 (1.05–2.35)
P for trend0.0840.0410.0420.013
  • a Cox proportional hazard models were used to estimate HRs and 95% CIs.

  • b Model 1: adjusted for age, sex, smoking status, alcohol intake, regular exercise, BMI, LDL cholesterol, HDL cholesterol, and triglycerides. Model 2: model 1 plus adjustment for hypertension, diabetes, history of heart disease, and history of stroke. Model 3: model 2 plus fatty liver.