Table 4.

Association of nonfasting triglycerides with incident CVD above or below an optimal threshold of 175 mg/dL.a

Time since last mealbnModel 1cModel 2dModel 3e
HR (95% CI)PHR (95% CI)PHR (95% CI)P
All nonfasting (0–8 h)63911.88 (1.52–2.33)<0.00011.36 (1.06–1.75)0.021.25 (0.96–1.62)0.10
0 to <4 h37972.05 (1.54–2.74)<0.00011.55 (1.10–2.18)0.011.41 (0.99–2.00)0.06
4 to <8 h25941.68 (1.21–2.32)0.0021.15 (0.78–1.70)0.471.05 (0.71–1.57)0.80
P for interactionf0.510.540.71
  • a Association with incident CVD above or below the optimal diagnostic threshold of 175 mg/dL for nonfasting triglycerides over a 17-year follow-up period, with adjusted models and stratified by time since last meal. To convert triglyceride concentrations to mmol/L, multiply by 0.0113.

  • b No interaction between hours since last meal and association of triglycerides with CVD events.

  • c Adjusted for age, history of hypertension, smoking, use of hormone therapy, and postmenopausal status.

  • d Adjusted for covariates in model 1 plus total cholesterol and HDL-C.

  • e Adjusted for covariates in model 2 plus diabetes mellitus, BMI, and hsCRP.

  • f P for interaction between hours since last meal (defined as 0 to <4 h vs 4 to <8 h) and triglycerides ≥175 mg/dL.