Table 1.

Baseline characteristics of the study cohort of patients with suspected acute coronary syndrome.a

cTnI below LoDb (n = 935)cTnI between LoD and 99th percentile (n = 85)cTnI above 99th percentile (n = 323)
Age, mean (SD), years59 (14)67 (13)66 (12)
Sex, males629/935 (67%)49/85 (58%)211/323 (65%)
Classical risk factors
    Body mass index >30248/867 (29%)19/77 (25%)79/298 (27%)
    Hypertension645/935 (69%)68/85 (80%)253/323 (78%)
    Diabetes mellitus153/935 (16%)21/85 (20%)72/323 (22%)
    Current smoking230/934 (25%)20/85 (24%)93/323 (29%)
    Dyslipidemia665/935 (71%)62/85 (73%)247/323 (76%)
    Parental CAD334/934 (36%)20/85 (24%)109/322 (34%)
    Known CAD303/934 (32%)40/85 (47%)123/323 (38%)
GRACE score variables
    Age, mean (SD), years59 (14)67 (13)66 (12)
    Heart rate, mean (SD)73 (15)73 (17)77 (17)
    Systolic blood pressure, mean (SD)142 (23)149 (28)144 (25)
    Creatinine, median (IQR)0.93 (0.81–1.06)1.00 (0.88–1.22)0.99 (0.87–1.21)
    Killipclass, 3-tuple(81%, 8%, 10%)(75%, 15%, 9%)(73%, 16%, 11%)
    ST elevation72/935 (8%)14/85 (16%)51/323 (16%)
    ST depression60/935 (6%)15/85% (18%)77/323 (24%)
Final diagnosis
    AMI47/938 (5%)41/105 (39%)226/279 (81%)
    ACS191/1087 (18%)46/105 (44%)304/357 (85%)
  • a Patient characteristics are given according to cTnI concentrations if determined using a contemporary sensitive assay. Data are presented as number with percentage, mean with SD, or median with IQR as appropriate.

  • b LoD denotes level of detection and 99th percentile of the diagnostic threshold concentration of the used cs-cTnI with 10 ng/L and 32 ng/L, respectively. CAD, coronary artery disease.