Characteristic | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | P^{a} | P for trend^{b} | ||||
---|---|---|---|---|---|---|---|---|---|---|

n | Value | n | Value | n | Value | n | Value | |||

cTnI range, ng/L | ||||||||||

Men | 1087 | 0.0–2.6 | 1087 | 2.7–3.7 | 1120 | 3.8–5.6 | 1137 | 5.7–610.8 | ||

Women | 1275 | 0.0–1.9 | 1264 | 2.0–2.7 | 1407 | 2.8–4.1 | 1335 | 4.2–363.1 | ||

Mean age, years (SD) | 2360 | 39.2 (12.6) | 2351 | 44.7 (14.0) | 2527 | 52.0 (14.6) | 2472 | 63.2 (15.3) | <0.001 | <0.001 |

Clinical characteristics | ||||||||||

Diabetes mellitus, n (%) | 2360 | 26 (1.1) | 2349 | 31 (1.3) | 2522 | 73 (2.9) | 2459 | 146 (5.9) | <0.001 | <0.001 |

Hypertension, n (%) | 2357 | 50 (2.1) | 2344 | 117 (5.0) | 2522 | 273 (10.8) | 2463 | 631 (25.6) | <0.001 | <0.001 |

Myocardial infarction, n (%) | 2356 | 12 (0.5) | 2348 | 16 (0.7) | 2519 | 46 (1.8) | 2455 | 208 (8.5) | <0.001 | <0.001 |

Current smoker, n (%) | 2345 | 807 (34.4) | 2330 | 689 (29.6) | 2500 | 746 (29.8) | 2434 | 492 (20.2) | <0.001 | 0.013 |

Mean systolic blood pressure, mmHg (SD) | 2353 | 126.1 (15.4) | 2341 | 131.1 (17.6) | 2571 | 137.8 (20.1) | 2459 | 150.3 (24.9) | <0.001 | <0.001 |

Laboratory measurements | ||||||||||

Mean eGFR, mL · min^{−1} · (1.73 m^{2})^{−1} (SD) | 2360 | 77.4 (12.0) | 2351 | 74.3 (12.1) | 2527 | 70.9 (12.2) | 2472 | 65.2 (14.4) | <0.001 | <0.001 |

Mean cholesterol, mg/dL (SD)^{c} | 2360 | 197 (40) | 2351 | 219 (41) | 2527 | 239 (44) | 2472 | 249 (50) | <0.001 | <0.001 |

Mean HDL cholesterol, mg/dL (SD) | 2360 | 56 (15) | 2351 | 54 (15) | 2524 | 53 (15) | 2472 | 53 (16) | <0.001 | <0.001 |

Geometric mean CRP, mg/L (95% CI) | 2360 | 0.61 (0.57–0.66) | 2350 | 0.81 (0.75–0.86) | 2525 | 0.96 (0.91–1.02) | 2469 | 1.32 (1.24–1.40) | <0.001 | <0.001 |

↵a χ

^{2}test was used for categorical variables, ANOVA for continuous variables.↵b Cochran–Armitage test was used for categorical variables. For continuous variables, each case was assigned a median inside of each quartile, and the correlation was calculated between the new variable and the category number.

↵c To convert cholesterol concentrations from mg/dL to mmol/L, multiply by 0.02586.