RT Journal Article
SR Electronic
T1 Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge
JF Clinical Chemistry
JO Clin. Chem.
FD American Association for Clinical Chemistry
SP 499
OP 502
VO 18
IS 6
A1 Friedewald, William T.
A1 Levy, Robert I.
A1 Fredrickson, Donald S.
YR 1972
UL http://clinchem.aaccjnls.org/content/18/6/499.abstract
AB A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented. The method involves measurements of fasting plasma total cholesterol, triglyceride, and high-density lipoprotein cholesterol concentrations, none of which requires the use of the preparative ultracentrifuge. Comparison of this suggested procedure with the more direct procedure, in which the ultracentrifuge is used, yielded correlation coefficients of .94 to .99, depending on the patient population compared.