March 2017; volume 63, issue 3
ON THE COVER Marijuana Gummy Bear. Although he may appear like candy, this bear means serious business. In the past, marijuana (cannabis) was consumed mostly by inhalation. Today, oral cannabis represents one-third of the consumed drug, and this route of administration is growing. Paralleling this growth, traffic safety has ascended the scale of urgency because cannabis-associated traffic accidents and fatalities have also increased. And so have the issues of testing and interpretation of results. Unlike roadside breath testing for alcohol, no such technology exists for cannabis. So, how can roadside cannabis testing be performed? Can oral fluid be used as an alternative since it is noninvasive and collectable in most situations? What does oral cannabis pharmacokinetics look like, and how does it correlate with blood concentrations? This issue of Clinical Chemistry contains a Special Report (and accompanying editorial) that looks at blood and oral fluid cannabinoid
pharmacokinetics, and evaluates oral fluid screening devices, to try to answer these questions. (See pages 629 and 647.) ©Reproduced with permission from maxpixel.freegreatpicture.com.
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