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Research ArticleArticle

Multiplexed Elimination of Wild-Type DNA and High-Resolution Melting Prior to Targeted Resequencing of Liquid Biopsies

Ioannis Ladas, Mariana Fitarelli-Kiehl, Chen Song, Viktor A. Adalsteinsson, Heather A. Parsons, Nancy U. Lin, Nikhil Wagle, G. Mike Makrigiorgos
DOI: 10.1373/clinchem.2017.272849 Published September 2017
Ioannis Ladas
Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA;
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Mariana Fitarelli-Kiehl
Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA;
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Chen Song
Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA;
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Viktor A. Adalsteinsson
The Broad Institute of MIT and Harvard, Cambridge, MA;
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Heather A. Parsons
Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
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Nancy U. Lin
Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
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Nikhil Wagle
Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
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G. Mike Makrigiorgos
Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA;
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  • For correspondence: mmakrigiorgos@lroc.harvard.edu
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Article Information

vol. 63 no. 10 1605-1613
DOI 
https://doi.org/10.1373/clinchem.2017.272849
PubMed 
28679646

Published By 
Clinical Chemistry
Print ISSN 
0009-9147
Online ISSN 
1530-8561
History 
  • Received for publication February 27, 2017
  • Accepted for publication May 12, 2017
  • Published online September 28, 2017.

Article Versions

  • Latest version (July 5, 2017 - 11:00).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2017 American Association for Clinical Chemistry

Author Information

  1. Ioannis Ladas1,†,
  2. Mariana Fitarelli-Kiehl1,†,
  3. Chen Song1,†,
  4. Viktor A. Adalsteinsson2,
  5. Heather A. Parsons3,
  6. Nancy U. Lin3,
  7. Nikhil Wagle3 and
  8. G. Mike Makrigiorgos1,*
  1. 1 Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA;
  2. 2 The Broad Institute of MIT and Harvard, Cambridge, MA;
  3. 3 Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  1. ↵* Address correspondence to this author at: Department of Radiation Oncology, Level L2, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115. Fax 617-582-6037; e-mail mmakrigiorgos{at}lroc.harvard.edu.
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Clinical Chemistry: 63 (10)
Vol. 63, Issue 10
October 2017
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Multiplexed Elimination of Wild-Type DNA and High-Resolution Melting Prior to Targeted Resequencing of Liquid Biopsies
Ioannis Ladas, Mariana Fitarelli-Kiehl, Chen Song, Viktor A. Adalsteinsson, Heather A. Parsons, Nancy U. Lin, Nikhil Wagle, G. Mike Makrigiorgos
Clinical Chemistry Oct 2017, 63 (10) 1605-1613; DOI: 10.1373/clinchem.2017.272849
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Multiplexed Elimination of Wild-Type DNA and High-Resolution Melting Prior to Targeted Resequencing of Liquid Biopsies
Ioannis Ladas, Mariana Fitarelli-Kiehl, Chen Song, Viktor A. Adalsteinsson, Heather A. Parsons, Nancy U. Lin, Nikhil Wagle, G. Mike Makrigiorgos
Clinical Chemistry Oct 2017, 63 (10) 1605-1613; DOI: 10.1373/clinchem.2017.272849

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