Clinical Chemistry: 60 (1)

January 2014; volume 60, issue 1

Preamble

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What's Different about Women's Health?
Ann M. Gronowski, JoAnn E. Manson, Elaine R. Mardis, Samia Mora, Catherine Y. Spong

Clinical Chemistry Jan 2014, 60 (1) 1-3; DOI: 10.1373/clinchem.2013.216598

Editorials

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Tumor Microenvironment–Released Peptides: Could They Form the Basis for an Early-Diagnosis Breast Cancer Test?
Eleftherios P. Diamandis

Clinical Chemistry Jan 2014, 60 (1) 4-6; DOI: 10.1373/clinchem.2013.216143
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High-Sensitivity Cardiac Troponin Assays: Isn't It Time for Equality?
Allan S. Jaffe, Fred S. Apple

Clinical Chemistry Jan 2014, 60 (1) 7-9; DOI: 10.1373/clinchem.2013.217927

Interview

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An Interview with Nancy Andrews
Misia Landau

Clinical Chemistry Jan 2014, 60 (1) 10-17; DOI: 10.1373/clinchem.2013.203711

Reflection

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The Long Gestation of the Modern Home Pregnancy Test
Glenn D. Braunstein

Clinical Chemistry Jan 2014, 60 (1) 18-21; DOI: 10.1373/clinchem.2013.202655

Perspective

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Retooling the Pap Smear for Ovarian and Endometrial Cancer Detection
Jamie Bakkum-Gamez, Sean Dowdy

Clinical Chemistry Jan 2014, 60 (1) 22-24; DOI: 10.1373/clinchem.2013.204933

Q&A

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The Ethical Implications of Preimplantation Genetic Diagnosis
Ann M. Gronowski, Richard T. Scott, Arthur L. Caplan, Lawrence J. Nelson

Clinical Chemistry Jan 2014, 60 (1) 25-28; DOI: 10.1373/clinchem.2013.202515

Clinical Case Study

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Premenopausal Amenorrhea: What's in a Number?
Robert D. Nerenz, Emily S. Jungheim, Christina M. Lockwood

Clinical Chemistry Jan 2014, 60 (1) 29-33; DOI: 10.1373/clinchem.2013.202499
Commentaries
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  Commentary
  Lawrence M. Nelson
  
  Clinical Chemistry Jan 2014, 60 (1) 33; DOI: 10.1373/clinchem.2013.217257
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  Commentary
  Betsy Hirsch
  
  Clinical Chemistry Jan 2014, 60 (1) 34; DOI: 10.1373/clinchem.2013.217265

Mini-Reviews

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Biomarkers in ACS and Heart Failure: Should Men and Women Be Interpreted Differently?
Shweta R. Motiwala, Amy Sarma, James L. Januzzi, Michelle L. O'Donoghue

Clinical Chemistry Jan 2014, 60 (1) 35-43; DOI: 10.1373/clinchem.2013.202531
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Sex Differences in the Metabolic Syndrome: Implications for Cardiovascular Health in Women
Aruna D. Pradhan

Clinical Chemistry Jan 2014, 60 (1) 44-52; DOI: 10.1373/clinchem.2013.202549
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Pharmacogenomic Testing and Personalized Treatment of Depression
Roy H. Perlis

Clinical Chemistry Jan 2014, 60 (1) 53-59; DOI: 10.1373/clinchem.2013.204446
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Ductal Carcinoma In Situ of the Breast: Can Biomarkers Improve Current Management?
John M.S. Bartlett, Sharon Nofech-Moses, Eileen Rakovitch

Clinical Chemistry Jan 2014, 60 (1) 60-67; DOI: 10.1373/clinchem.2013.207183

Reviews

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Menopausal Hormone Therapy and Cardiovascular Disease Risk: Utility of Biomarkers and Clinical Factors for Risk Stratification
Shari S. Bassuk, JoAnn E. Manson

Clinical Chemistry Jan 2014, 60 (1) 68-77; DOI: 10.1373/clinchem.2013.202556
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Integration of Noninvasive DNA Testing for Aneuploidy into Prenatal Care: What Has Happened Since the Rubber Met the Road?
Diana W. Bianchi, Louise Wilkins-Haug

Clinical Chemistry Jan 2014, 60 (1) 78-87; DOI: 10.1373/clinchem.2013.202663
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Cardiovascular Disease Risk Prediction in Women: Is There a Role for Novel Biomarkers?
Nina P. Paynter, Brendan M. Everett, Nancy R. Cook

Clinical Chemistry Jan 2014, 60 (1) 88-97; DOI: 10.1373/clinchem.2013.202796
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The Emerging Genomic Landscape of Endometrial Cancer
Matthieu Le Gallo, Daphne W. Bell

Clinical Chemistry Jan 2014, 60 (1) 98-110; DOI: 10.1373/clinchem.2013.205740
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Lynch Syndrome Presenting as Endometrial Cancer
Laura J. Tafe, Eleanor R. Riggs, Gregory J. Tsongalis

Clinical Chemistry Jan 2014, 60 (1) 111-121; DOI: 10.1373/clinchem.2013.206888
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The Omics of Triple-Negative Breast Cancers
Hong Xu, Peter Eirew, Sarah C. Mullaly, Samuel Aparicio

Clinical Chemistry Jan 2014, 60 (1) 122-133; DOI: 10.1373/clinchem.2013.207167

Opinions

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Thrombophilia Testing in Women with Venous Thrombosis: The 4 P's Approach
Mary Cushman

Clinical Chemistry Jan 2014, 60 (1) 134-137; DOI: 10.1373/clinchem.2013.202648
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The Affordable Care Act and the Opportunity to Improve Prevention in Women: How to Make the Most of the Law
Paula A. Johnson, Therese Fitzgerald

Clinical Chemistry Jan 2014, 60 (1) 138-140; DOI: 10.1373/clinchem.2013.203703
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Diagnosis of Gestational Diabetes Mellitus: It Is Time for International Consensus
David B. Sacks

Clinical Chemistry Jan 2014, 60 (1) 141-143; DOI: 10.1373/clinchem.2013.206920
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Genomics of Cervical Cancer and the Role of Human Papillomavirus Pathobiology
Denise Uyar, Janet Rader

Clinical Chemistry Jan 2014, 60 (1) 144-146; DOI: 10.1373/clinchem.2013.212985
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Global Women's Health: Progress toward Reducing Sex-Based Health Disparities
Nawal M. Nour

Clinical Chemistry Jan 2014, 60 (1) 147-150; DOI: 10.1373/clinchem.2013.213181

Point/Counterpoint

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Point: New Trichs for “Old” Dogs: Prospects for Expansion of Trichomonas vaginalis Screening
Erik Munson

Clinical Chemistry Jan 2014, 60 (1) 151-154; DOI: 10.1373/clinchem.2013.210021
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Counterpoint: Screening for Trichomoniasis—Where's the Evidence of Benefit?
Mark A. Klebanoff

Clinical Chemistry Jan 2014, 60 (1) 155-157; DOI: 10.1373/clinchem.2013.210039

Articles

Proteomics and Protein Markers
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  Prognostic Performance of a High-Sensitivity Cardiac Troponin I Assay in Patients with Non–ST-Elevation Acute Coronary Syndrome
  Erin A. Bohula May, Marc P. Bonaca, Petr Jarolim, Elliott M. Antman, Eugene Braunwald, Robert P. Giugliano, L. Kristin Newby, Marc S. Sabatine, David A. Morrow
  
  Clinical Chemistry Jan 2014, 60 (1) 158-164; DOI: 10.1373/clinchem.2013.206441
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  Circulating Fetuin-A and Risk of Ischemic Stroke in Women
  Monik C. Jiménez, Qi Sun, Markus Schürks, Frank B. Hu, JoAnn E. Manson, Kathryn M. Rexrode
  
  Clinical Chemistry Jan 2014, 60 (1) 165-173; DOI: 10.1373/clinchem.2013.212597
Endocrinology and Metabolism
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  Age, Body Mass, Usage of Exogenous Estrogen, and Lifestyle Factors in Relation to Circulating Sex Hormone–Binding Globulin Concentrations in Postmenopausal Women
  Atsushi Goto, Brian H. Chen, Yiqing Song, Jane Cauley, Steven R. Cummings, Ghada N. Farhat, Marc Gunter, Linda Van Horn, Barbara V. Howard, Rebecca Jackson, Jennifer Lee, Kathryn M. Rexrode, Simin Liu
  
  Clinical Chemistry Jan 2014, 60 (1) 174-185; DOI: 10.1373/clinchem.2013.207217
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  Circulating 25-Hydroxyvitamin D, IRS1 Variant rs2943641, and Insulin Resistance: Replication of a Gene–Nutrient Interaction in 4 Populations of Different Ancestries
  Ju-Sheng Zheng, Laurence D. Parnell, Caren E. Smith, Yu-Chi Lee, Aziza Jamal-Allial, Yiyi Ma, Duo Li, Katherine L. Tucker, José M. Ordovás, Chao-Qiang Lai
  
  Clinical Chemistry Jan 2014, 60 (1) 186-196; DOI: 10.1373/clinchem.2013.215251
Cancer Diagnostics
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  Prognostic Significance of Metastasis-Related MicroRNAs in Early Breast Cancer Patients with a Long Follow-up
  Athina Markou, George M. Yousef, Efstathios Stathopoulos, Vassilis Georgoulias, Evi Lianidou
  
  Clinical Chemistry Jan 2014, 60 (1) 197-205; DOI: 10.1373/clinchem.2013.210542
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  Circulating U2 Small Nuclear RNA Fragments as a Novel Diagnostic Tool for Patients with Epithelial Ovarian Cancer
  Jan Dominik Kuhlmann, Alexander Baraniskin, Stephan A. Hahn, Frank Mosel, Maren Bredemeier, Pauline Wimberger, Rainer Kimmig, Sabine Kasimir-Bauer
  
  Clinical Chemistry Jan 2014, 60 (1) 206-213; DOI: 10.1373/clinchem.2013.213066
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  Prognostic Relevance of Viable Circulating Tumor Cells Detected by EPISPOT in Metastatic Breast Cancer Patients
  Jean-Marie Ramirez, Tanja Fehm, Mattea Orsini, Laure Cayrefourcq, Thierry Maudelonde, Klaus Pantel, Catherine Alix-Panabières
  
  Clinical Chemistry Jan 2014, 60 (1) 214-221; DOI: 10.1373/clinchem.2013.215079
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  Genetic Variants in the Fibroblast Growth Factor Pathway as Potential Markers of Ovarian Cancer Risk, Therapeutic Response, and Clinical Outcome
  Qing H. Meng, Enping Xu, Michelle A.T. Hildebrandt, Dong Liang, Karen Lu, Yuanqing Ye, Elizabeth A. Wagar, Xifeng Wu
  
  Clinical Chemistry Jan 2014, 60 (1) 222-232; DOI: 10.1373/clinchem.2013.211490
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  Circulating Proteolytic Products of Carboxypeptidase N for Early Detection of Breast Cancer
  Yaojun Li, Yueguo Li, Tao Chen, Anna S. Kuklina, Paul Bernard, Francisco J. Esteva, Haifa Shen, Mauro Ferrari, Ye Hu
  
  Clinical Chemistry Jan 2014, 60 (1) 233-242; DOI: 10.1373/clinchem.2013.211953
Molecular Diagnostics and Genetics
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  Circulating Fetal Cell-Free DNA Fractions Differ in Autosomal Aneuploidies and Monosomy X
  Richard P. Rava, Anupama Srinivasan, Amy J. Sehnert, Diana W. Bianchi
  
  Clinical Chemistry Jan 2014, 60 (1) 243-250; DOI: 10.1373/clinchem.2013.207951
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  Maternal Mosaicism Is a Significant Contributor to Discordant Sex Chromosomal Aneuploidies Associated with Noninvasive Prenatal Testing
  Yanlin Wang, Yan Chen, Feng Tian, Jianguang Zhang, Zhuo Song, Yi Wu, Xu Han, Wenjing Hu, Duan Ma, David Cram, Weiwei Cheng
  
  Clinical Chemistry Jan 2014, 60 (1) 251-259; DOI: 10.1373/clinchem.2013.215145
General Clinical Chemistry
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  Measurement of Unconjugated Estriol in Serum by Liquid Chromatography–Tandem Mass Spectrometry and Assessment of the Accuracy of Chemiluminescent Immunoassays
  Xianzhang Huang, David C. Spink, Erasmus Schneider, Helen Ling, Alex J. Rai, Thomas G. Rosano, Baorong Chen, Zhimin (Tim) Cao
  
  Clinical Chemistry Jan 2014, 60 (1) 260-268; DOI: 10.1373/clinchem.2013.212126

Citation Classic

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The Triple Test
Nicholas J. Wald

Clinical Chemistry Jan 2014, 60 (1) 269-270; DOI: 10.1373/clinchem.2013.212050

Letter to the Editor

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High-Sensitivity Cardiac Troponin I for Predicting Death in a Female Emergency Department Population
Peter A. Kavsak, Colleen Shortt, Greg Pond, Andrew Worster

Clinical Chemistry Jan 2014, 60 (1) 271-273; DOI: 10.1373/clinchem.2013.211557

Clinical Chemist

What Is Your Guess?
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  Mysterious Stones
  Janice Giasson, Yu Chen
  
  Clinical Chemistry Jan 2014, 60 (1) 274-275; DOI: 10.1373/clinchem.2013.205427
News & Views
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  Call for Nominations
  Clinical Chemistry Jan 2014, 60 (1) 275;
The Best of Clinical Chemistry
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  The Top 10 Most Downloaded Clinical Case Studies
  Clinical Chemistry Jan 2014, 60 (1) 276;
Technology Corner
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  Picturing Cervical Cancer
  Molly Webster, Vikram Sheel Kumar
  
  Clinical Chemistry Jan 2014, 60 (1) 277-279; DOI: 10.1373/clinchem.2013.217521
Unveiling the Right Side
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  Osteoporosis of the Bone—At Sea without a Lifeboat
  Usha Anand
  
  Clinical Chemistry Jan 2014, 60 (1) 280-281; DOI: 10.1373/clinchem.2013.216119
Quo Vadis
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  Quo Vadis?
  Clinical Chemistry Jan 2014, 60 (1) 282-283;
Science in the Arts
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  Florence Nightingale: Nurse, Writer, and Consummate Politician
  Marek H. Dominiczak
  
  Clinical Chemistry Jan 2014, 60 (1) 284-285; DOI: 10.1373/clinchem.2013.213561

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Table of Contents

Preamble

Editorials

Interview

Reflection

Perspective

Q&A

Clinical Case Study

Commentaries

Mini-Reviews

Reviews

Opinions

Point/Counterpoint

Articles

Proteomics and Protein Markers

Endocrinology and Metabolism

Cancer Diagnostics

Molecular Diagnostics and Genetics

General Clinical Chemistry

Citation Classic

Letter to the Editor

Clinical Chemist

What Is Your Guess?

News & Views

The Best of Clinical Chemistry

Technology Corner

Unveiling the Right Side

Quo Vadis

Science in the Arts

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