Clinical Chemistry: 58 (12)

December 2012; volume 58, issue 12

Editorials

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Comparing Multiple Measures of Glycemia: How to Transition from Biomarker to Diagnostic Test?
Robert M. Cohen, David B. Sacks

Clinical Chemistry Dec 2012, 58 (12) 1615-1617; DOI: 10.1373/clinchem.2012.196139
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PCR-Based Multiparametric Assays in Single Cells
Spyros Darmanis, Caroline Gallant, Ulf Landegren

Clinical Chemistry Dec 2012, 58 (12) 1618-1619; DOI: 10.1373/clinchem.2012.195867
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Understanding the Role of Immunoaffinity-Based Mass Spectrometry Methods for Clinical Applications
Bradley L. Ackermann

Clinical Chemistry Dec 2012, 58 (12) 1620-1622; DOI: 10.1373/clinchem.2012.193714

Perspective

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Homocysteine and Cardiovascular Risk: The Perils of Reductionism in a Complex System
Per Magne Ueland, Joseph Loscalzo

Clinical Chemistry Dec 2012, 58 (12) 1623-1625; DOI: 10.1373/clinchem.2012.187286

Q&A

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NHLBI Integrated Guidelines on Cardiovascular Disease Risk Reduction: Can We Clarify the Controversy about Cholesterol Screening and Treatment in Childhood?
Sarah D. de Ferranti, Stephen R. Daniels, Matthew Gillman, Louis Vernacchio, Jorge Plutzky, Annette L. Baker

Clinical Chemistry Dec 2012, 58 (12) 1626-1630; DOI: 10.1373/clinchem.2012.182089

Clinical Case Study

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Prescription Compliance or Illicit Designer Drug Abuse?
Matthew S. Petrie, Kara L. Lynch, Alan H.B. Wu, Angela A. Steinhardt, Gary L. Horowitz

Clinical Chemistry Dec 2012, 58 (12) 1631-1634; DOI: 10.1373/clinchem.2011.174649
Commentaries
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  Commentary
  Michael Ganetsky
  
  Clinical Chemistry Dec 2012, 58 (12) 1634-1635; DOI: 10.1373/clinchem.2012.182261
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  Commentary
  Michael C. Milone
  
  Clinical Chemistry Dec 2012, 58 (12) 1635; DOI: 10.1373/clinchem.2012.184127

Review

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Beyond Diagnostic Accuracy: The Clinical Utility of Diagnostic Tests
Patrick M.M. Bossuyt, Johannes B. Reitsma, Kristian Linnet, Karel G.M. Moons

Clinical Chemistry Dec 2012, 58 (12) 1636-1643; DOI: 10.1373/clinchem.2012.182576

Opinion

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Medicine Unplugged: The Future of Laboratory Medicine
Ravi Komatireddy, Eric J. Topol

Clinical Chemistry Dec 2012, 58 (12) 1644-1647; DOI: 10.1373/clinchem.2012.194324

Articles

Lipids, Lipoproteins, and Cardiovascular Risk Factors
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  Associations of Alternative Markers of Glycemia with Hemoglobin A_1c and Fasting Glucose
  Stephen P. Juraschek, Michael W. Steffes, Elizabeth Selvin
  
  Clinical Chemistry Dec 2012, 58 (12) 1648-1655; DOI: 10.1373/clinchem.2012.188367
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  ELISA System for Human Endothelial Lipase
  Tatsuro Ishida, Kazuya Miyashita, Mamoru Shimizu, Noriaki Kinoshita, Kenta Mori, Li Sun, Tomoyuki Yasuda, Shigeyuki Imamura, Katsuyuki Nakajima, Kimber L. Stanhope, Peter J. Havel, Ken-ichi Hirata
  
  Clinical Chemistry Dec 2012, 58 (12) 1656-1664; DOI: 10.1373/clinchem.2012.187914
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  Longitudinal Studies of Cardiac Troponin I in a Large Cohort of Healthy Children
  Gus Koerbin, Julia M. Potter, Walter P. Abhayaratna, Richard D. Telford, Tony Badrick, Fred S. Apple, Allan S. Jaffe, Peter E. Hickman
  
  Clinical Chemistry Dec 2012, 58 (12) 1665-1672; DOI: 10.1373/clinchem.2012.192054
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  Distribution and Clinical Correlates of the Interleukin Receptor Family Member Soluble ST2 in the Framingham Heart Study
  Erin E. Coglianese, Martin G. Larson, Ramachandran S. Vasan, Jennifer E. Ho, Anahita Ghorbani, Elizabeth L. McCabe, Susan Cheng, Michael G. Fradley, Dana Kretschman, Wei Gao, George O'Connor, Thomas J. Wang, James L. Januzzi
  
  Clinical Chemistry Dec 2012, 58 (12) 1673-1681; DOI: 10.1373/clinchem.2012.192153
Molecular Diagnostics and Genetics
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  Quantitative PCR Analysis of DNA, RNAs, and Proteins in the Same Single Cell
  Anders Ståhlberg, Christer Thomsen, David Ruff, Pierre Åman
  
  Clinical Chemistry Dec 2012, 58 (12) 1682-1691; DOI: 10.1373/clinchem.2012.191445
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  COLD-PCR and Innovative Microarray Substrates for Detecting and Genotyping MPL Exon 10 W515 Substitutions
  Angela Brisci, Francesco Damin, Daniela Pietra, Silvia Galbiati, Sabrina Boggi, Ilaria Casetti, Elisa Rumi, Marcella Chiari, Mario Cazzola, Maurizio Ferrari, Laura Cremonesi
  
  Clinical Chemistry Dec 2012, 58 (12) 1692-1702; DOI: 10.1373/clinchem.2012.192708
Endocrinology and Metabolism
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  Performance Criteria for Testosterone Measurements Based on Biological Variation in Adult Males: Recommendations from the Partnership for the Accurate Testing of Hormones
  Yeo-Min Yun, Julianne Cook Botelho, Donald W. Chandler, Alex Katayev, William L. Roberts, Frank Z. Stanczyk, Hubert W. Vesper, Jon M. Nakamoto, Luigi Garibaldi, Nigel J. Clarke, Robert L. Fitzgerald
  
  Clinical Chemistry Dec 2012, 58 (12) 1703-1710; DOI: 10.1373/clinchem.2012.186569

Brief Communication

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Characterizing Antibody Cross-reactivity for Immunoaffinity Purification of Analytes prior to Multiplexed Liquid Chromatography–Tandem Mass Spectrometry
Thomas J. Laha, Frederick G. Strathmann, Zhican Wang, Ian H. de Boer, Kenneth E. Thummel, Andrew N. Hoofnagle

Clinical Chemistry Dec 2012, 58 (12) 1711-1716; DOI: 10.1373/clinchem.2012.185827

Citation Classic

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Introducing Tissue Microarrays to Molecular Pathology
Ollie P. Kallioniemi, Juha Kononen, Guido Sauter

Clinical Chemistry Dec 2012, 58 (12) 1717-1718; DOI: 10.1373/clinchem.2012.188748

Letters to the Editor

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Removal of 3-Epi-25-Hydroxyvitamin D₃ Interference by Liquid Chromatography–Tandem Mass Spectrometry Is Not Required for the Measurement of 25-Hydroxyvitamin D₃ in Patients Older than 2 Years
Michael J.P. Wright, David J. Halsall, Brian G. Keevil

Clinical Chemistry Dec 2012, 58 (12) 1719-1720; DOI: 10.1373/clinchem.2012.191460
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Standardizing Next-Generation Sequencing Experiments and Analysis Methods
Jasmin H. Bavarva, Wyatt McMahon, Megha J. Bavarva, Enusha Karunasena, Harold R. Garner

Clinical Chemistry Dec 2012, 58 (12) 1720-1722; DOI: 10.1373/clinchem.2012.189241
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Addressing Laboratory Workforce Issues in Australia
Tony C. Badrick, Andrew St. John

Clinical Chemistry Dec 2012, 58 (12) 1722-1723; DOI: 10.1373/clinchem.2012.195792

Correction

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Correction
Clinical Chemistry Dec 2012, 58 (12) 1724; DOI: 10.1373/clinchem.2012.196022

Clinical Chemist

What Is Your Guess?
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  I Dare You!
  Ann M. Gronowski, Mitchell G. Scott
  
  Clinical Chemistry Dec 2012, 58 (12) 1725-1726; DOI: 10.1373/clinchem.2012.191221
News & Views
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  Clinical Chemistry's 2013 Special Issue: Cancer
  Clinical Chemistry Dec 2012, 58 (12) 1726; DOI: 10.1373/clinchem.2012.197178
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  The Third Universal Definition of Myocardial Infarction—Moving Forward
  Allan S. Jaffe, Fred S. Apple
  
  Clinical Chemistry Dec 2012, 58 (12) 1727-1728; DOI: 10.1373/clinchem.2012.196832
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  CDC Recommendations: Good Laboratory Practices for Biochemical Genetic Testing and Newborn Screening for Inherited Metabolic Disorders
  Shahram Shahangian, Bin Chen
  
  Clinical Chemistry Dec 2012, 58 (12) 1728; DOI: 10.1373/clinchem.2012.195362
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  Whole-Genome Sequencing: Ready for Prime Time?
  David T. Miller, Ahmed A. Alfares
  
  Clinical Chemistry Dec 2012, 58 (12) 1729-1730; DOI: 10.1373/clinchem.2012.196543
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  Clinical Chemistry's Invited Reviewers 2012
  Clinical Chemistry Dec 2012, 58 (12) 1730-1732;
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  “Reaching Out to the World” Appreciation
  Clinical Chemistry Dec 2012, 58 (12) 1732-1734; DOI: 10.1373/clinchem.2012.196535
Unveiling the Right Side
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  It's a Small World … Looking from a Different Perspective
  Kristina Davis
  
  Clinical Chemistry Dec 2012, 58 (12) 1734-1735; DOI: 10.1373/clinchem.2012.197152
Quo Vadis?
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  Quo Vadis?
  Clinical Chemistry Dec 2012, 58 (12) 1736-1737; DOI: 10.1373/clinchem.2012.197392
Science in the Arts
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  Hospital Building That Merges Science and Art: Alvar Aalto
  Marek H. Dominiczak
  
  Clinical Chemistry Dec 2012, 58 (12) 1738-1739; DOI: 10.1373/clinchem.2012.182055

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Table of Contents

Editorials

Perspective

Q&A

Clinical Case Study

Commentaries

Review

Opinion

Articles

Lipids, Lipoproteins, and Cardiovascular Risk Factors

Molecular Diagnostics and Genetics

Endocrinology and Metabolism

Brief Communication

Citation Classic

Letters to the Editor

Correction

Clinical Chemist

What Is Your Guess?

News & Views

Unveiling the Right Side

Quo Vadis?

Science in the Arts

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