Clinical Chemistry: 52 (4)

April 2006; volume 52, issue 4

Editorials

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Why Commutability Matters
W. Greg Miller, Gary L. Myers, Robert Rej

Clinical Chemistry Apr 2006, 52 (4) 553-554; DOI: 10.1373/clinchem.2005.063511
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How Should We Measure the Albumin in Urine?
Theodore Peters

Clinical Chemistry Apr 2006, 52 (4) 555-556; DOI: 10.1373/clinchem.2005.065284
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Is the DNA Sequence the Gold Standard in Genetic Testing? Quality of Molecular Genetic Tests Assessed
Egbert Bakker

Clinical Chemistry Apr 2006, 52 (4) 557-558; DOI: 10.1373/clinchem.2005.066068
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Tracking Microchimeric DNA in Plasma to Diagnose and Manage Organ Transplant Rejection
Lee Ann Baxter-Lowe, Michael P. Busch

Clinical Chemistry Apr 2006, 52 (4) 559-561; DOI: 10.1373/clinchem.2005.064766

Reviews

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Urine Markers as Possible Tools for Prostate Cancer Screening: Review of Performance Characteristics and Practicality
Heiko Müller, Hermann Brenner

Clinical Chemistry Apr 2006, 52 (4) 562-573; DOI: 10.1373/clinchem.2005.062919
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Mechanisms in Protein O-Glycan Biosynthesis and Clinical and Molecular Aspects of Protein O-Glycan Biosynthesis Defects: A Review
Suzan Wopereis, Dirk J. Lefeber, Éva Morava, Ron A. Wevers

Clinical Chemistry Apr 2006, 52 (4) 574-600; DOI: 10.1373/clinchem.2005.063040
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Biomarkers of Oxidative Damage in Human Disease
Isabella Dalle-Donne, Ranieri Rossi, Roberto Colombo, Daniela Giustarini, Aldo Milzani

Clinical Chemistry Apr 2006, 52 (4) 601-623; DOI: 10.1373/clinchem.2005.061408

Molecular Diagnostics and Genetics

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Antiprimer Quenching-Based Real-Time PCR and Its Application to the Analysis of Clinical Cancer Samples
Jin Li, Fengfei Wang, Harvey Mamon, Matthew H. Kulke, Lyndsay Harris, Elizabeth Maher, Lilin Wang, G. Mike Makrigiorgos

Clinical Chemistry Apr 2006, 52 (4) 624-633; DOI: 10.1373/clinchem.2005.063321
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Quantification of mRNA in Whole Blood by Assessing Recovery of RNA and Efficiency of cDNA Synthesis
Masato Mitsuhashi, Shigeru Tomozawa, Katsuya Endo, Atsushi Shinagawa

Clinical Chemistry Apr 2006, 52 (4) 634-642; DOI: 10.1373/clinchem.2005.048983
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Detection of Mucopolysaccharidosis Type II by Measurement of Iduronate-2-Sulfatase in Dried Blood Spots and Plasma Samples
Caroline J. Dean, Michelle R. Bockmann, John J. Hopwood, Doug A. Brooks, Peter J. Meikle

Clinical Chemistry Apr 2006, 52 (4) 643-649; DOI: 10.1373/clinchem.2005.061838

Evidence-Based Laboratory Medicine and Test Utilization

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Estimation and Application of Biological Variation of Urinary δ-Aminolevulinic Acid and Porphobilinogen in Healthy Individuals and in Patients with Acute Intermittent Porphyria
Aasne K. Aarsand, Per Hyltoft Petersen, Sverre Sandberg

Clinical Chemistry Apr 2006, 52 (4) 650-656; DOI: 10.1373/clinchem.2005.060772

Hemostasis and Thrombosis

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P-Selectin- and CD63-Exposing Platelet Microparticles Reflect Platelet Activation in Peripheral Arterial Disease and Myocardial Infarction
P. Marc van der Zee, Éva Biró, Yung Ko, Robbert J. de Winter, C. Erik Hack, Augueste Sturk, Rienk Nieuwland

Clinical Chemistry Apr 2006, 52 (4) 657-664; DOI: 10.1373/clinchem.2005.057414
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Utility of Thrombin-Generation Assay in the Screening of Factor V G1691A (Leiden) and Prothrombin G20210A Mutations and Protein S Deficiency
Nathalie Hézard, Lobna Bouaziz-Borgi, Marie-Geneviève Remy, Philippe Nguyen

Clinical Chemistry Apr 2006, 52 (4) 665-670; DOI: 10.1373/clinchem.2005.063339

Proteomics and Protein Markers

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Rapid Proteome Analysis of Bronchoalveolar Lavage Samples of Lifelong Smokers and Never-Smokers by Micro-Scale Liquid Chromatography and Mass Spectrometry
Amelie Plymoth, Ziping Yang, Claes-Göran Löfdahl, Ann Ekberg-Jansson, Magnus Dahlbäck, Thomas E. Fehniger, György Marko-Varga, William S. Hancock

Clinical Chemistry Apr 2006, 52 (4) 671-679; DOI: 10.1373/clinchem.2005.060715
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B-Type Natriuretic Peptide (BNP) and N-Terminal Pro-BNP in Obese Patients without Heart Failure: Relationship to Body Mass Index and Gastric Bypass Surgery
John V. St. Peter, Guilford G. Hartley, MaryAnn M. Murakami, Fred S. Apple

Clinical Chemistry Apr 2006, 52 (4) 680-685; DOI: 10.1373/clinchem.2005.062562

Cancer Diagnostics

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Clinical Utility of an Automated Immunochemiluminometric Thyroglobulin Assay in Differentiated Thyroid Carcinoma
Adrienne C.M. Persoon, Johannes M.W. Van Den Ouweland, Juergen Wilde, Ido P. Kema, Bruce H.R. Wolffenbuttel, Thera P. Links

Clinical Chemistry Apr 2006, 52 (4) 686-691; DOI: 10.1373/clinchem.2005.060095

Drug Monitoring and Toxicology

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Pretreatment Plasma Folate Modulates the Pharmacodynamic Effect of High-Dose Methotrexate in Children with Acute Lymphoblastic Leukemia and Non-Hodgkin Lymphoma: “Folate Overrescue” Concept Revisited
Jaroslav Sterba, Ladislav Dusek, Regina Demlova, Dalibor Valik

Clinical Chemistry Apr 2006, 52 (4) 692-700; DOI: 10.1373/clinchem.2005.061150

Endocrinology and Metabolism

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Variations in Porphobilinogen and 5-Aminolevulinic Acid Concentrations in Plasma and Urine from Asymptomatic Carriers of the Acute Intermittent Porphyria Gene with Increased Porphyrin Precursor Excretion
Ylva Floderus, Eliane Sardh, Christer Möller, Claes Andersson, Lillan Rejkjaer, Dan E.H. Andersson, Pauline Harper

Clinical Chemistry Apr 2006, 52 (4) 701-707; DOI: 10.1373/clinchem.2005.058198

Automation and Analytical Techniques

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Fast In Vivo Microextraction: A New Tool for Clinical Analysis
Florin Marcel Musteata, Mihaela L. Musteata, Janusz Pawliszyn

Clinical Chemistry Apr 2006, 52 (4) 708-715; DOI: 10.1373/clinchem.2005.064758

Laboratory Management

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Methodologic European External Quality Assurance for DNA Sequencing: The EQUALseq Program
Parviz Ahmad-Nejad, Alexandra Dorn-Beineke, Ulrike Pfeiffer, Joachim Brade, Wolf-Jochen Geilenkeuser, Simon Ramsden, Mario Pazzagli, Michael Neumaier

Clinical Chemistry Apr 2006, 52 (4) 716-727; DOI: 10.1373/clinchem.2005.061572
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Benchmark for Evaluating the Quality of DNA Sequencing: Proposal from an International External Quality Assessment Scheme
Simon J. Patton, Andrew J. Wallace, Rob Elles

Clinical Chemistry Apr 2006, 52 (4) 728-736; DOI: 10.1373/clinchem.2005.061887

Technical Briefs

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Osmolality Gaps: Diagnostic Accuracy and Long-Term Variability
John Krahn, Annu Khajuria

Clinical Chemistry Apr 2006, 52 (4) 737-739; DOI: 10.1373/clinchem.2005.057695
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Multiplex Tetra-Primer Amplification Refractory Mutation System PCR to Detect 6 Common Germline Mutations of the MUTYH Gene Associated with Polyposis and Colorectal Cancer
Patrizia Piccioli, Martina Serra, Viviana Gismondi, Simona Pedemonte, Fabrizio Loiacono, Sonia Lastraioli, Lucio Bertario, Maria De Angioletti, Liliana Varesco, Rosario Notaro

Clinical Chemistry Apr 2006, 52 (4) 739-743; DOI: 10.1373/clinchem.2005.060137
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Differentiation of Amphetamine/Methamphetamine and Other Cross-Immunoreactive Sympathomimetic Amines in Urine Samples by Serial Dilution Testing
Alison Woodworth, Al N. Saunders, John W. Koenig, Thomas P. Moyer, John Turk, Dennis J. Dietzen

Clinical Chemistry Apr 2006, 52 (4) 743-746; DOI: 10.1373/clinchem.2005.060616
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Relationship between Cortisol Increment and Basal Cortisol: Implications for the Low-Dose Short Adrenocorticotropic Hormone Stimulation Test
Suhail A.R. Doi, Ibrahim Lasheen, Khaldoon Al-Humood, Kamal A.S. Al-Shoumer

Clinical Chemistry Apr 2006, 52 (4) 746-749; DOI: 10.1373/clinchem.2005.061267
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Total Polyphenol Intake Estimated by a Modified Folin–Ciocalteu Assay of Urine
Elena Roura, Cristina Andrés-Lacueva, Ramon Estruch, Rosa M. Lamuela-Raventós

Clinical Chemistry Apr 2006, 52 (4) 749-752; DOI: 10.1373/clinchem.2005.063628
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Influence of Imprecision on ROC Curve Analysis for Cardiac Markers
Peter Kupchak, Alan H.B. Wu, Farooq Ghani, L. Kristen Newby, E. Magnus Ohman, Robert H. Christenson

Clinical Chemistry Apr 2006, 52 (4) 752-753; DOI: 10.1373/clinchem.2005.064477
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Analysis of Methylmalonic Acid in Plasma by Liquid Chromatography–Tandem Mass Spectrometry
Anne Schmedes, Ivan Brandslund

Clinical Chemistry Apr 2006, 52 (4) 754-757; DOI: 10.1373/clinchem.2005.058586
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Unexpected Serum Parathyroid Hormone Profiles in Some Patients with Primary Hyperparathyroidism
Philippe Boudou, Fidaa Ibrahim, Catherine Cormier, Emile Sarfati, Jean-Claude Souberbielle

Clinical Chemistry Apr 2006, 52 (4) 757-760; DOI: 10.1373/clinchem.2005.060962
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Analytical Performance and Diagnostic Accuracy of Immunometric Assays for the Measurement of Circulating Oxidized LDL
Paul Holvoet, Elizabeth Macy, Michele Landeloos, Dan Jones, Jenny S. Nancy, Frans Van de Werf, Russell P. Tracy

Clinical Chemistry Apr 2006, 52 (4) 760-764; DOI: 10.1373/clinchem.2005.064337

Letters to the Editor

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Organic Solvents Compromise Performance of Internal Standard (Ascomycin) in Proficiency Testing of Mass Spectrometry-Based Assays for Tacrolimus
Kimberly L. Napoli

Clinical Chemistry Apr 2006, 52 (4) 765-766; DOI: 10.1373/clinchem.2005.061341
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Influence of Sampling and Storage Conditions on B-Type Natriuretic Peptide Immunoreactivity for 3 Automated Assays
Damien Gruson, Michel F. Rousseau, Virginie de Coninck, Sylvie A. Ahn, Jean-Marie Ketelslegers

Clinical Chemistry Apr 2006, 52 (4) 766-767; DOI: 10.1373/clinchem.2005.062455
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Use of B-Type Natriuretic Peptide Testing in a Community Teaching Hospital 4 Years After Implementation and Agreement of Results with Discharge Diagnoses
Michael A. Linden, Fred S. Apple

Clinical Chemistry Apr 2006, 52 (4) 767-768; DOI: 10.1373/clinchem.2005.063404
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Pediatric Tube Direct Sampling by the Abbott Architect Integrated ci8200 Chemistry/Immunochemistry Analyzer
Maaike W. Rautenberg, Wouter W. van Solinge, Juliska J. Heunks, Ron H. Stokwielder, Eef G.W.M. Lentjes, Hans Kemperman

Clinical Chemistry Apr 2006, 52 (4) 768-770; DOI: 10.1373/clinchem.2005.063867
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Six Sigma and Calculated Laboratory Tests
Abdurrahman Coskun

Clinical Chemistry Apr 2006, 52 (4) 770-771; DOI: 10.1373/clinchem.2005.064311
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Validation of Breast Cancer Biomarkers Identified by Mass Spectrometry
Eleftherios P. Diamandis

Clinical Chemistry Apr 2006, 52 (4) 771-772; DOI: 10.1373/clinchem.2005.064972
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Validation of Breast Cancer Biomarkers Identified by Mass Spectrometry: Some of the authors of the article cited above respond:
Jinong Li, Zhen Zhang, Daniel W. Chan

Clinical Chemistry Apr 2006, 52 (4) 772; DOI: 10.1373/clinchem.2005.066142
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Pretreatment of Serum with Penicillamine: Effects on Capillary Electrophoresis Patterns and on Immunonephelometric Measurement of Immunoglobulins
Ilenia Infusino, Paola Luraschi, Mauro Panteghini, Carlo Franzini

Clinical Chemistry Apr 2006, 52 (4) 772-774; DOI: 10.1373/clinchem.2005.062711
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Use of Serum on Guthrie Cards in Screening for Congenital Disorders of Glycosylation
Hubert A. Carchon, Célestin Nsibu Ndosimao, Sandra Van Aerschot, Jaak Jaeken

Clinical Chemistry Apr 2006, 52 (4) 774-775; DOI: 10.1373/clinchem.2005.063305
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Prenatal Diagnosis of Guanidinoacetate Methyltransferase Deficiency: Increased Guanidinoacetate Concentrations in Amniotic Fluid
David Cheillan, Gajja S. Salomons, Cécile Acquaviva, Catherine Boisson, Philippe Roth, Marie-Pierre Cordier, Laurence François, Cornelis Jakobs, Christine Vianey-Saban

Clinical Chemistry Apr 2006, 52 (4) 775-777; DOI: 10.1373/clinchem.2005.065185
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Smoking Acutely Increases Plasma Ghrelin Concentrations
Demosthenes Bouros, Argyris Tzouvelekis, Stavros Anevlavis, Michael Doris, Stavros Tryfon, Marios Froudarakis, Vasiliki Zournatzi, Asterios Kukuvitis

Clinical Chemistry Apr 2006, 52 (4) 777-778; DOI: 10.1373/clinchem.2005.065243
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Effect of Plasmodium falciparum Parasitemia on Erythrocyte Zinc Protoporphyrin
Girish S. Hiremath, David J. Sullivan, Abhai K. Tripathi, Robert E. Black, Sunil Sazawal

Clinical Chemistry Apr 2006, 52 (4) 778-779; DOI: 10.1373/clinchem.2006.066316
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Multiplex PCR Assay for the Identification and Differentiation of all Brucella Species and the Vaccine Strains Brucella abortus S19 and RB51 and Brucella melitensis Rev1
David García-Yoldi, Clara M. Marín, María J. de Miguel, Pilar M. Muñoz, José L. Vizmanos, Ignacio López-Goñi

Clinical Chemistry Apr 2006, 52 (4) 779-781; DOI: 10.1373/clinchem.2005.062596
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Influence of PON1 Polymorphisms on the Association between Serum Paraoxonase 1 and Homocysteinemia in a General Population
Michelle M. Murphy, Judit Marsillach, Jordi Camps, Joan Fernández-Ballart, Bharti Mackness, Michael Mackness, Natàlia Ferré, Jorge Joven

Clinical Chemistry Apr 2006, 52 (4) 781-782; DOI: 10.1373/clinchem.2005.064212
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Tumor M2 Pyruvate Kinase as a Stool Marker for Colorectal Cancer: Stability at Room Temperature and Implications for Application in the Screening Setting
Ulrike Haug, Moritz N. Wente, Christoph M. Seiler, Dietrich Rothenbacher, Markus W. Büchler, Hermann Brenner

Clinical Chemistry Apr 2006, 52 (4) 782-784; DOI: 10.1373/clinchem.2005.062752
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Potentially Inappropriate Repeat Laboratory Testing in Inpatients
Robert C. Hawkins

Clinical Chemistry Apr 2006, 52 (4) 784-785; DOI: 10.1373/clinchem.2005.064139
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Glycerol and Ethanol in Red Wine Are Responsible for Urate-Related Increases in Plasma Antioxidant Capacity
Darko Modun, Ivana Music, Visnja Katalinic, Zeljko Dujic, Mladen Boban

Clinical Chemistry Apr 2006, 52 (4) 785-787; DOI: 10.1373/clinchem.2005.065656
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Effect of Delayed Processing on High-Sensitivity C-Reactive Protein
Lilli B. Link, Judith S. Jacobson

Clinical Chemistry Apr 2006, 52 (4) 787-788; DOI: 10.1373/clinchem.2006.066738

Book, Software, and Web Site Reviews

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DORA 05-07: Directory of Rare Analyses. Jocelyn M. Hicks and Donald S. Young, editors. Washington, DC: AACC Press, 2005, 650 pp., $125.00 ($99.00 AACC members), softcover. ISBN 1-594250-31-6.
Robert Rej

Clinical Chemistry Apr 2006, 52 (4) 789; DOI: 10.1373/clinchem.2005.058115
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The Evolution from Protein Chemistry to Proteomics: Basic Science to Clinical Application. Roger L. Lundblad. Boca Raton, FL: CRC Press, 2006, 295 pp., $139.95, hardcover. ISBN 0-8493-9678-6.
Glen L. Hortin

Clinical Chemistry Apr 2006, 52 (4) 789-790; DOI: 10.1373/clinchem.2005.063875
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Medical Biomethods Handbook. John M. Walker and Ralph Rapley. Totowa, NJ: Humana Press, 2005, 656 pp. plus CD-ROM, hardcover, $150.00. ISBN 1-58829-288-6.
Mario Plebani

Clinical Chemistry Apr 2006, 52 (4) 790; DOI: 10.1373/clinchem.2005.058990

The Clinical Chemist

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The Clinical Chemist: 2006 AACC Award Recipients
David E. Bruns

Clinical Chemistry Apr 2006, 52 (4) 791; DOI: 10.1373/clinchem.2006.069542
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The Clinical Chemist: Masahide Sasaki, MD, PhD (August 27, 1933–September 23, 2005)
Robin A. Felder

Clinical Chemistry Apr 2006, 52 (4) 791-792; DOI: 10.1373/clinchem.2006.067686

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Table of Contents

Editorials

Reviews

Molecular Diagnostics and Genetics

Evidence-Based Laboratory Medicine and Test Utilization

Hemostasis and Thrombosis

Proteomics and Protein Markers

Cancer Diagnostics

Drug Monitoring and Toxicology

Endocrinology and Metabolism

Automation and Analytical Techniques

Laboratory Management

Technical Briefs

Letters to the Editor

Book, Software, and Web Site Reviews

The Clinical Chemist

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